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Fucoidan, a special intercellular polysaccharide, which exists in
the cell wall matrix, is the unique biological activity matter in
brown algae.
We extract the fucoidan from the Laminaria japonicia.
The product, which is hydrosoluble heteropolysaccharide, mainly consists of sulfuric
ester- Fucose, and also have little quantities of galactose,
Mannose, xylose, arabinose, saccharic-aldehyded acid. So
it¡¯s also called algin
or fucoidan & laminaran, the major effective
ingredient is ¦Á-L-fucose-4-sulfuric
ester.
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Fucoidan is an excellent raw material of
health-foods and
drug
medicine.
Because
of
natural Organic sulfate
radical, it has
characteristic of
high molecular compound
containing
the negative ion.
Studies showed that it have many physiologically actives,
such as inhibiting
blood clotting, lowering the blood fats,
repelling chronic
renal-failure, anti-tumor,
anti-virus, regenerating
tissue, Suppressing gastric ulcer,
enhancing
bodies¡¯ immunity, etc.Fucoidan is an immunomodulator
which have immediate effects on Macrophage and T-cell,with
obvious pharmacological
activities
of
inhibiting blood clotting and promoting fibrinolysis. Fucose
or its
degradative
offspring
can
induce cancer-cells-apoptosis,
so it
can
be
used
on revulsant and anticancer-drug. The generation of
Cytokines |
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-growth can help all kinds of cells to grow , repair the
damaged tissue and an organ or tissue functions failure.Because
polysaccharides has the anticoagulant effect, which vails the
patient who has hyper-blood-viscosity, it can be made to drugs and
health products in counteracting
or preventing the thrombos
It also has an efficacy against lowering
cholesterol levels and
blood sugar levels, can
overcome side effects of normal medicine. It can be used in
treatment of chronic renal failure, especially in an early
phase, improving the functions of renaland enhancing creatinine
clearance.
It also can be used as cements and reduction additives of
metallic ion. For example, It can abate the absorption of Pb by
70%.
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The general pharmacology research indicated:
the
dose
of100mg/Kg¡¢ 300mg/Kg
medicine to doped up dog, the
dog had no obviouse effects on blood
pressure
and.
heart-electricity.
400mg/Kg¡¢800mg/Kg
had no obviouse effects on Mouse
nervous system. The acute toxicity
test indicated that, Mouse
intravenous injection LD50 is 515.3¡À39.8 mg/Kg; The
little mouse fills the stomach with medicine LD50>
4g/Kg, the big mouse fills the stomach with medicine LD50>
4g
/Kg.
The long-term toxicity test indicated
that,By2.5,0.9,0.3g/Kg/day,filling the stomach for the big mouse
obviously with the medicine for 6 months and a months and a month
recovery period,hematologytargets do not have been influenced
obviously, except the hemoglutination time targets, And no obvious
pathological changes are discovered in the internal organs
coefficient during the histo-pathology inspection. The orally dose
of 60mg/Kg for 180days is the security non-toxic dosage.
AMES
showed that Fucoidan do not have sudden change effection on the
gene.
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Product:
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FUCOIDAN
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Material:
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Laminaria japonicia Aresch
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Characteristics:
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white
or light yellow powder,
pellucidly dissolved in water
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Main
usage:
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1¡¢material
of traditional Chinese drugs used in kidney disease.
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| 2¡¢it
can be used in health-foods and drinks.
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| 3¡¢it
can be used in cosmetic
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| Standard: |
enterprise
standard (Q/RJJK
001-2005)
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| Packing: |
innerpacking£ºPE
bottle,
500g
/bottle
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Outpacking:
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paper drum (20bottle/drum) or carton (10bottle/carton)
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Preservation:
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keeo away from air, light and humidity,
Quality
guarantee for three years
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Quality
Standard for Fucoidan
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Item
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Norm
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Fucose£¨%£©
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¡Ý15.0
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Organic SO42-£¨%£©
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¡Ý20.0
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MOISTURE£¨%£©
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¡Ü10.0
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Heavy Metals£¨pb£©£¨mg/kg£©
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¡Ü20.0
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Inorganic
arsenic£¨mg/kg£©
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¡Ü2.0
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Total bacteria Count
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£¼1000/g
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Coliform
Count
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£¼30
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Pathogenic
bacteria
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none
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Mercury
(mg/Kg)
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¡Ü0.3 |
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Cadmium(mg/Kg) |
¡Ü0.2 |
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